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  1. Simple, diverse univariate spectrophotometric methods were developed and validated for the determination of amlodipine besylate (AM), perindopril arginine (PE), and indapamide (ID). The first method involved d...

    Authors: Aya T. Soudi
    Citation: BMC Chemistry 2025 19:33
    Content type: Research Published on:

  2. Carivalan® pharmaceutical formulation, which includes carvedilol and ivabradine hydrochloride, is commonly prescribed for alleviating pain associated with angina. Solid contact ion-selective electrodes with wide ...

    Authors: Nermine V. Fares, Haitham A. El Fiky, Dina A. Ahmed, Maha F. Abd El Ghany, Amr M. Badawey and Mahmoud A. Tantawy
    Citation: BMC Chemistry 2025 19:32
    Content type: Research Published on:

  3. In this study, cobalt titanate nanoparticles (CoTiO₃ NPs) were synthesized and applied as a photocatalyst to degrade atrazine. Scanning electron microscopic (SEM) analysis showed irregularly shaped particles p...

    Authors: Jeremiah Suleiman Nuhu, Femi Emmanuel Awe, Rajni Garg, Rishav Garg, Nnabuk Okon Eddy and Hazratullah Paktin
    Citation: BMC Chemistry 2025 19:31
    Content type: Research Published on:

  4. Presently, humanity is confronted with a range of diseases that have high death rates, especially those linked to cancerous growths. Several enzymes and proteins have been discovered as highly attractive targe...

    Authors: Mahmoud A. El Hassab, Wagdy M. Eldehna, Ghaneya S. Hassan and Sahar M. Abou-Seri
    Citation: BMC Chemistry 2025 19:30
    Content type: Research Published on:

  5. Novel N-arylacetamides 2a–f were synthesized based on benzo[d]thiazole scaffold. The compounds 2a–c underwent Knoevenagel condensation through green synthetic method with different aromatic aldehydes and pyrazole...

    Authors: Nadia Hanafy Metwally, Galal Hamza Elgemeie, Aya Ragab Abdelrazek and Salwa Magdy Eldaly
    Citation: BMC Chemistry 2025 19:29
    Content type: Research Published on:

  6. A large set of antimalarial molecules (N ~ 15k) was employed from ChEMBL to build a robust random forest (RF) model for the prediction of antiplasmodial activity. Rather than depending on high throughput screenin...

    Authors: Mukul Kore, Dimple Acharya, Lakshya Sharma, Shruthi Sridhar Vembar and Sandeep Sundriyal
    Citation: BMC Chemistry 2025 19:28
    Content type: Research Published on:

  7. For paediatric patients suffering from neurofibromatosis, Selumetinib (SEL) is the only approved drug. Here an original ecofriendly and high pace method is introduced using 96- microwell spectrophotometric ass...

    Authors: Sarah Alrubia, Wafa A. AlShehri, Awwad A. Radwan, Nourah Z. Alzoman and Ibrahim A. Darwish
    Citation: BMC Chemistry 2025 19:27
    Content type: Research Published on:

  8. The study of green analytical chemistry has garnered significant attention in the context of mitigating global environmental contamination. In this study, we present two methodologies for environmentally frien...

    Authors: Maimana A. Magdy, Maha M. Abdelrahman, Doaa G. Mohamed and Amal B. Ahmed
    Citation: BMC Chemistry 2025 19:26
    Content type: Research Published on:

  9. This work intended to assess the disinfection efficacy of hypochlorous acid (HA) and silver nanoparticles (AgNP) disinfectants in disinfecting the dental unit waterlines (DUWL) during comprehensive oral treatm...

    Authors: Tingting Yin, Qiaowen Li, Huan Sun, Jin Zheng, Yuanyuan Wang, Yi Luo and Li Wang
    Citation: BMC Chemistry 2025 19:25
    Content type: Research Published on:

  10. The structural and electronic behavior of thiosemicarbazone (TSC)-based metal complexes of Mn (II), Fe (II), and Ni (II) have been investigated. The synthesized metal complexes were characterized using element...

    Authors: Doaa S. El‑Sayed, Shaymaa S. Hassan, Liblab S. Jassim, Ali Abdullah Issa, Firas AL-Oqaili, Mustafa k. Albayaty, Buthenia A. Hasoon, Majid S. Jabir, Khetam H. Rasool and Hemmat A. Elbadawy
    Citation: BMC Chemistry 2025 19:24
    Content type: Research Published on:

  11. An ecofriendly, effective, and selective spectrofluorimetric approach for natamycin analysis was developed using fluorescamine as a fluorogenic probe. Natamycin is the only topical ocular antifungal medication...

    Authors: Sayed M. Derayea and Fatma F. Mohammed
    Citation: BMC Chemistry 2025 19:23
    Content type: Research Published on:

  12. Trimethylamine-N-oxide (TMAO) is gut microbiota-derived metabolite, plays a critical role in human health and diseases such as metabolic, cardiovascular, colorectal cancer and, neurological disorders. Binding ...

    Authors: Awadhesh Kumar Verma, Payal Gulati, GBVS Lakshmi, Anand Mohan, Neeta Raj Sharma, Pratima R. Solanki and Anil Kumar
    Citation: BMC Chemistry 2025 19:22
    Content type: Research Published on:

  13. Mn2+ is an essential cation extensively utilized in various industrial processes, including electrolytic manganese production, manganese dioxide manufacturing, and zinc processing. It also poses significant envir...

    Authors: Yanli Xu, Fuyuan Xu, Yong Liu, Guangbin Zhu, Ying Chen and Ning Duan
    Citation: BMC Chemistry 2025 19:21
    Content type: Research Published on:

  14. Shilajit, a natural substance used in traditional and modern medicine, has gained prominence as a vital component in dietary supplements. Concerns regarding its use in complementary medicine have arisen due to...

    Authors: Elham Kamgar, Joanna Zembrzuska, Wlodzimierz Zembrzuski and Massoud Kaykhaii
    Citation: BMC Chemistry 2025 19:20
    Content type: Research Published on:

  15. As the common antibacterial drugs in folic acid oral liquid, parabens are listed as mandatory substances in the quality standard. Both the Chinese Pharmacopoeia and the United States Pharmacopoeia use high per...

    Authors: Wenhong Wu, Ying Liang, Renbang Zhao, Yude Shi, Jiahui Hou, Jiumei Peng, Jiadi Pan, Xiaoyi Li and Jingjing Zhou
    Citation: BMC Chemistry 2025 19:19
    Content type: Research Published on:

  16. Water is one of the vital needs of life. However, due to rapid industrialization, urbanization and lack of awareness, the world population now facing the threat of water shortage. To ensure that future living ...

    Authors: Safaa A. Hussein, Gharib M. Taha, F. A. Adam and Marwa A. Moghazy
    Citation: BMC Chemistry 2025 19:18
    Content type: Original Article Published on:

  17. White and Green Analytical Chemistry are innovative approaches in analytical chemistry that prioritize both sustainability and efficiency. Together, these approaches aim to advance scientific research while mi...

    Authors: Mennah M. Abd Elwahab, Samar Saad, Zeinab A. Sheribah and Nahed El-Enany
    Citation: BMC Chemistry 2025 19:17
    Content type: Research Published on:

  18. Malaria is the extensive health concern in sub-Saharan Africa, with Plasmodium falciparum being the most lethal strain. The continued emergence of drug-resistant P. falciparum advocates for the development of new...

    Authors: Lindiwe Khumbuzile Zuma, Ofentse Jacob Pooe, Nonduduzo Hlengiwe Mabaso, John Alake, Vincent A. Obakachi, Sinethemba Yakobi, Nothando Gasa, Rajshekhar Karpoormath and Mthokozisi Simelane
    Citation: BMC Chemistry 2025 19:16
    Content type: Research Published on:

  19. Lidocaine poses challenges when it comes to direct spectrophotometric measurement due to the lack of sharp peak within its spectra in zero-order. This lack of a distinct peak makes it difficult to accurately q...

    Authors: Naglaa Ahmed, Ahmed Hemdan, Hala ZaaZaa and Maha Galal
    Citation: BMC Chemistry 2025 19:15
    Content type: Research Published on:

  20. A simple, rapid, and reproducible high-performance liquid chromatography (HPLC) method has been developed and validated for the determination of β-sitosterol in the pharmaceutical dosage form of moist exposed ...

    Authors: Haya I. Aljohar, Abdullah M. Al-Hossaini, Seham A. Alzammay, Samiah Alhabardi, Hadir M. Maher and Aya R. Ahmed
    Citation: BMC Chemistry 2025 19:14
    Content type: Research Published on:

  22. Surfactant-modified biochar is a viable adsorbent for eliminating Cr(VI) from synthetic wastewater. The biochar obtained from the zea mays plant (BC) was tailored with sodium dodecyl sulfate (SDS) as an anionic s...

    Authors: Azza M. Shaker, Mohamed Khedawy, Abeer A. Moneer, Nabila M. El-Mallah and Mohamed S. Ramadan
    Citation: BMC Chemistry 2025 19:12
    Content type: Research Published on:

  23. Coronavirus disease 2019 (COVID-19), an extremely contagious illness, has posed enormous challenges to healthcare systems around the world. Although the evidence on COVID-19 management is growing, antiviral me...

    Authors: Amal B. Ahmed, Maha M. Abdelrahman and Fadwa H. Edrees
    Citation: BMC Chemistry 2025 19:11
    Content type: Research Published on:

  25. Tirofiban hydrochloride is used to inhibit platelet aggregation, which has a significant impact on the treatment of congestive heart failure the most common cause of death according to WHO. Therefore, its quan...

    Authors: Mohamed. Rizk, Maha Mahmoud Abou El-Alamin, Ola Abd Elkhalek and Hassan A. M. Hendawy
    Citation: BMC Chemistry 2025 19:9
    Content type: Research Published on:

  26. Novel, «green» and simple visible spectrophotometric procedures for the determination of six dihydropyridines CCBs (amlodipine besylate (AML), lacidipine (LAC), levamlodipine besylate (LAML), nifedipine (NIF), ni...

    Authors: Mariana Horyn, Liubomyr Kryskiw, Tetyana Kucher, Nadiya Zarivna, Olha Poliak and Liliya Logoyda
    Citation: BMC Chemistry 2025 19:8
    Content type: Research Published on:

  27. Co-administration of COVID-19 RNA polymerase inhibitors, remdesivir and favipiravir, has synergistic benefits. Together they reduce viral load and inflammation more effectively than either drug used alone. Cor...

    Authors: Rehab M. Abdelfatah, Esraa H. Abdelmomen, Eglal A. Abdelaleem, Refaat H. Abdelmoety and Aml A. Emam
    Citation: BMC Chemistry 2025 19:7
    Content type: Research Published on:

  28. The development of a newly fabricated ion-selective electrode (ISE) solid-contacted type for the determination of prucalopride succinate represents a significant advancement in analytical chemistry, particular...

    Authors: Marwa T. Saad, Shereen A. Boltia, Taghreed A. Fattah and Hala E. Zaazaa
    Citation: BMC Chemistry 2025 19:6
    Content type: Research Published on:

  30. Although the antiallergic properties of compounds such as CAPE, Melatonin, Curcumin, and Vitamin C have been poorly discussed by experimental studies, the antiallergic properties of these famous molecules have...

    Authors: Velid Unsal, Erkan Oner, Reşit Yıldız and Başak Doğru Mert
    Citation: BMC Chemistry 2025 19:4
    Content type: Research Published on:

  31. This study investigates the phenolic compounds (PC), volatile compounds (VC), and fatty acids (FA) of extra virgin olive oil (EVOO) derived from the Turkish olive variety “Sarı Ulak”, along with ADMET, DFT, mo...

    Authors: Velid Unsal, Reşit Yıldız, Aziz Korkmaz, Başak Doğru Mert, Cemile Gunbegi Calıskan and Erkan Oner
    Citation: BMC Chemistry 2025 19:3
    Content type: Research Published on:

  32. Mood disorders affect the daily lives of millions of people worldwide. The search for more efficient therapies for mood disorders remains an active field of research. In silico approaches can accelerate the se...

    Authors: Valeria V. Kleandrova, M. Natália D. S. Cordeiro and Alejandro Speck-Planche
    Citation: BMC Chemistry 2025 19:2
    Content type: Research Published on:

  33. Multiple sclerosis (MS) is a complex autoimmune disease of the central nervous system with an unknown etiology. While disease-modifying therapies can slow progression, there is a need for more effective treatm...

    Authors: Fozia Bashir Farooq, Nazeran Idrees, Esha Noor, Nouf Abdulrahman Alqahtani and Muhammad Imran
    Citation: BMC Chemistry 2025 19:1
    Content type: Research Published on:

  34. Magnetic activated carbon has been proved its separation ability to overcome a main drawback of activated carbon powder. However, effect of magnetization method on characterizations and Chromium (VI) adsorptio...

    Authors: Tran Tuyet Ngan, Ngo Thi Thuan, Nguyen Thi Thu Ngan, Tran Bao Ngoc Minh and Doan Hoai Linh
    Citation: BMC Chemistry 2024 18:251
    Content type: Research Published on:

  35. A simple and green chemometrics-assisted spectrophotometric technique has beendeveloped and validated for the determination of antipyrine (ANT) and benzocaine HCl (BEN) along with the official impurity of ANT,...

    Authors: Khadiga M. Kelani, Maha A. Hegazy, Amal M. Hassan and Ahmed H. Nadim
    Citation: BMC Chemistry 2024 18:250
    Content type: Research Published on:

  36. In virtual drug screening, consensus docking is a standard in-silico approach consisting of a combined result from optimized docking experiments, a minimum of two results combination. Therefore, consensus dock...

    Authors: Thanet Pitakbut, Jennifer Munkert, Wenhui Xi, Yanjie Wei and Gregor Fuhrmann
    Citation: BMC Chemistry 2024 18:249
    Content type: Research Published on:

  37. In the present study, ohmic heating system was developed for the pasteurization of liquid egg white. A batch reactor system was designed with a capacity of 100 ml and operated at varied gradients of voltage (2...

    Authors: M. Balakrishnan, A. Lilly Prasanna, A. Ramalakshmi, V. Vishnu Priya, P. Preetha and K. Thangavel
    Citation: BMC Chemistry 2024 18:248
    Content type: Research Published on:

  38. To enhance the accuracy of virtual screening for bromodomain-containing protein 4 (BRD4) inhibitors, two docking protocols and seven scoring functions were compared. A total of 73 crystal structures of BRD4 (B...

    Authors: Junmin Dong and Xiaohua Hao
    Citation: BMC Chemistry 2024 18:247
    Content type: Research Published on:

  39. This study investigates the chemical interactions and mechanical characteristics of composites made of polystyrene reinforced with biochar. Polystyrene-based resin (PBR) was combined with plantain peel-derived...

    Authors: Adewale George Adeniyi, Sulyman A. Abdulkareem, Ebuka Chizitere Emenike, Ashraf M.M. Abdelbacki, Mubarak A. Amoloye, Kingsley O. Iwuozor, Abdelrahman O. Ezzat, Favour O. Eleregbe and Ifeoluwa Peter Oyekunle
    Citation: BMC Chemistry 2024 18:246
    Content type: Research Published on:

  40. A novel electrochemical probe is developed to detect amlodipine (AMD) in unprocessed plasma samples. The fabrication process involves the synthesis of platinum nanocubes (Pt NCs) and Mn(TPDCA)2 complexes, which a...

    Authors: Saeedeh Khadivi-Derakhshan, Mohammad Abbasi, Amirhossein Akbarzadeh, Mahtab Pirouzmand and Jafar Soleymani
    Citation: BMC Chemistry 2024 18:245
    Content type: Research Published on:

  41. The antibiotic resistance and biofilm formation by bacterial pathogens has led to failure in infections elimination. This study aimed to assess the antibacterial and anti-biofilm properties of novel synthesize...

    Authors: Elham Zarenezhad, Esmaeil Behmard, Raziyeh Karami, Somayeh Behrouz, Mahrokh Marzi, Abdolmajid Ghasemian and Mohammad Navid Soltani Rad
    Citation: BMC Chemistry 2024 18:244
    Content type: Research Published on:

  42. This Study focuses on the preparation of sustainable and efficient Chitosan catalyst for the removal of three organic pollutants, 17β-Estradiol (E2), 17α-ethynyl estradiol (EE2) and triclosan (TCS) from water....

    Authors: Ajibola A. Bayode, Samson. O. Akpotu, Martins O. Omorogie, Eny Maria Vieira and Emmanuel I. Unuabonah
    Citation: BMC Chemistry 2024 18:243
    Content type: Research Published on:

  43. Dihydrofolate reductase (DHFR) is an enzyme that plays a crucial role in folate metabolism, which is essential for cell growth and division. DHFR has been identified as a molecular target for numerous diseases du...

    Authors: Renu Sehrawat, Ritu Pasrija, Priyanka Rathee, Deepika Kumari and Anurag Khatkar
    Citation: BMC Chemistry 2024 18:242
    Content type: Research Published on:

  44. PI3K-α mutation plays a critical role in cancer development, notably in breast cancer, particularly within HR + /HER2- subtypes. These mutations drive tumor growth and survival by activating the PI3K/AKT/mTOR ...

    Authors: Ajay Mili, Sumit Birangal, Jyothi Giridhar, Krishnadas Nandakumar and Richard Lobo
    Citation: BMC Chemistry 2024 18:241
    Content type: Research Published on:

  45. Herrin, three Gemini cationic surfactants related to benzo[d]thiazol-3-ium bromide with variable hydrocarbon chain lengths (TBC n = 6, 12, and 18) were synthesized successfully and confirmed by using IR and 1HNMR...

    Authors: Farid I. El-Dossoki, Mohamed A. Migahed, Mahmoud M. Gouda and Samir A. Abd El-Maksoud
    Citation: BMC Chemistry 2024 18:240
    Content type: Research Published on:

  46. This study explores the use of green solvent systems by investigating the solubility and thermodynamic properties of xanthone (1) in triglyceride-based tricaprin (2) and tricaprylin (3) mixtures, aiming to rep...

    Authors: Hua Liu, Johnson Stanslas, Jiaoyan Ren, Norhidayah Binti Suleiman and Gun Hean Chong
    Citation: BMC Chemistry 2024 18:239
    Content type: Research Published on:

  47. Posaconazole (PCZ) is a triazole antifungal agent with a broad-spectrum activity. Our research aims to present a novel approach by combining a 2-level fractional factorial design and machine learning to optimi...

    Authors: Fereshteh Bayat, Ali Hashemi Baghi, Zahra Abbasian, Simin Dadashzadeh, Reza Aboofazeli and Azadeh Haeri
    Citation: BMC Chemistry 2024 18:238
    Content type: Research Published on:

  48. This study represents a comparison among the performances of four multivariate procedures: partial least square (PLS) and artificial neural networks (ANN) in addition to support vector regression (SVR) and ext...

    Authors: Mahmoud M. Elkhoudary, Aya A. Marie, Sherin F. Hammad, Mohamed M. Salim and Amira H. Kamal
    Citation: BMC Chemistry 2024 18:237
    Content type: Research Published on:

  49. Hypoxia-inducible factors (HIFs) are transcription factors that regulate erythropoietin (EPO) synthesis and red blood cell (RBC) production. Prolyl-4-hydroxylase domain (PHD) enzymes are key regulators of HIF’...

    Authors: Abrar Mohammad Sayaf, Kafila Kousar, Muhammad Suleman, Norah A. Albekairi, AbdulRahman Alshammari, Anwar Mohammad, Abbas Khan, Abdelali Agouni and Kar Kheng Yeoh
    Citation: BMC Chemistry 2024 18:236
    Content type: Research Published on:

  50. Breast cancer remains a leading cause of mortality among women worldwide. Our current research focuses on identifying effective therapeutic agents by targeting the human aromatase enzyme. Aromatase inhibitors ...

    Authors: Mohamed A. Kotb, Islam Ahmed Abdelmawgood and Ibrahim M. Ibrahim
    Citation: BMC Chemistry 2024 18:235
    Content type: Research Published on:
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BMC Chemistry

ISSN: 2661-801X

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