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  1. This study presents a new method for simultaneously quantifying a complex anti-migraine formulation containing five components (ergotamine, propyphenazone, caffeine, camylofin, and mecloxamine) using UV spectr...

    Authors: Ahmed Emad F. Abbas, Nahla A. Abdelshafi, Mohammed Gamal, Michael K. Halim, Basmat Amal M. Said, Ibrahim A. Naguib, Mohmeed M. A. Mansour, Samir Morshedy and Yomna A. Salem
    Citation: BMC Chemistry 2024 18:233
    Content type: Research Published on:

  2. Two accurate, precise and robust multivariate chemometric methods were developed for the simultaneous determination of montelukast sodium (MON), rupatadine fumarate (RUP) and desloratadine (DES). These methods...

    Authors: Marco M. Z. Sharkawi, Nehal F. Farid, Moataz H. Hassan and Said A. Hassan
    Citation: BMC Chemistry 2024 18:232
    Content type: Research Published on:

  3. The ternary combination like omeprazole (OMP), amoxicillin (AMX), and rifabutin (RFB) was approved by the FDA in November 2019 for combating Helicobacter pylori infections and ulcers caused by this infection. ...

    Authors: S. P. Ashnah Baffinsha, Vijayageetha Ragupathi and Hemanth Kumar Chanduluru
    Citation: BMC Chemistry 2024 18:231
    Content type: Research Published on:

  4. Two simple, valid and green chromatographic based techniques are developed in the present work for first time to simultaneously analyze the recently approved combination of Aspirin (ASP) with the novel gastro-...

    Authors: Mona M. Abdel Moneim and Mohamed M. A. Hamdy
    Citation: BMC Chemistry 2024 18:230
    Content type: Research Published on:

  5. Hybridization of spirooxindole with different pharmacophores such as triazole and heterocycle such as thiophene and furan moiety was achieved by the [3 + 2] cycloaddition (32CA) reaction approach. Structural i...

    Authors: Abdulmajeed Abdullah Alayyaf, M. Ali, Moayad Abdullah Alwehaibi, Muhanna K. Al-Muhanna, Saied M. Soliman, Mar Ríos-Gutiérrez, Matti Haukka and Assem Barakat
    Citation: BMC Chemistry 2024 18:229
    Content type: Research Published on:

  6. In this study, the chemoselective synthesis of two new thiophene derivatives is presented. The structure of newly synthesized thiophenes derivatives; ethyl 4-acetyl-3-phenyl-5-(phenylamino)thiophene-2-carboxyl...

    Authors: Abdullatif Bin Muhsinah, Mohammed M. Alharbi, Nabila A. Kheder, Saied M. Soliman, Hazem A. Ghabbour, Naglaa S. Mahmoud, Ismail A. Elhaty and Yahia N. Mabkhot
    Citation: BMC Chemistry 2024 18:228
    Content type: Research Published on:

  7. This study reveals one-step green synthesis of plant inspired silver nanoparticles (Ag-NPs). The synthesis procedure relies on the bio-reduction of Ag+ to Ag0 using orange waste (orange peel) extract as cheap, re...

    Authors: Yasmeen E. Mostafa, Fawzi Elsebaei and Mohammed El-Sayed Metwally
    Citation: BMC Chemistry 2024 18:227
    Content type: Research Published on:

  8. A set of innovative N-amino-5-cyano-6-pyridones derivatives was developed and produced using one-pot three-component procedures. The evaluated molecules were examined for their antimicrobial efficacy. Based on th...

    Authors: Omkulthom Al Kamaly, Amel S. Younes, Marwa F. Harras, Rehab Sabour, Aisha A. Alsfouk and Mona H. Ibrahim
    Citation: BMC Chemistry 2024 18:226
    Content type: Research Published on:

  9. Elevated Arsenic and Chromium levels in surface and ground waters are a significant health concern in several parts of the world. Chitosan quinoxaline Schiff base (CsQ) and cross-linked chitosan quinoxaline Sc...

    Authors: Huda E. Abdelwahab, Mohammed Elhag and Mohamed M. El Sadek
    Citation: BMC Chemistry 2024 18:225
    Content type: Research Published on:

  10. This research explores the enhancement of polyethersulfone (PES) membranes through the incorporation of chitosan derived from the lignicolous fungus Ganoderma sp. Utilizing wet phase inversion and solution castin...

    Authors: Hilya N. Iman, Henry Susilo, Adhi Satriyatama, Ignatius D. M. Budi, Kiki A. Kurnia, I. G. Wenten and K. Khoiruddin
    Citation: BMC Chemistry 2024 18:224
    Content type: Research Published on:

  11. As a springboard to explore novel potent inhibitors of cholinesterase enzymes (AChE and BChE) responsible for causing Alzheimer disorder, the current study was conducted to synthesize pyrrole derived triazole ...

    Authors: Shoaib Khan, Tayyiaba Iqbal, Muhammad Bilal Khan, Rafaqat Hussain, Yousaf Khan and Hany W. Darwish
    Citation: BMC Chemistry 2024 18:223
    Content type: Research Published on:

  12. In this work, the rapid and efficient preparation of isolated galloyl glucoside tautomer free radical inhibitors was investigated using Saxifraga tangutica as a raw material. Four highly polar galloyl glucoside t...

    Authors: Yingying Tong, Ming Chu, Jia Zhou, Qilan Wang, Gang Li, A. M. Abd El-Aty and Jun Dang
    Citation: BMC Chemistry 2024 18:222
    Content type: Research Published on:

  14. Aminothiazoles are the important class of chemical groups which have proven their broad range of biological activities. A novel aminothiazole (21MAT) was quantified in analytical solutions using a high-perform...

    Authors: Vinay N. Basavanakatti, Mohammad Ali, D.R. Bharathi, Sheikh Murtuja, Barij Nayan Sinha, Venkatesan Jayaprakash and Faiyaz Shakeel
    Citation: BMC Chemistry 2024 18:220
    Content type: Research Published on:

  15. Quetiapine fumarateis a typical antipsychotic with a short half-life of 6 h and is administered multiple times daily. In this study, a copolymer for controlled delivery of quetiapine fumarate will be developed...

    Authors: Takwa E. Ellakwa, Ahmad S. Abu-Khadra and Doha El-Sayed Ellakwa
    Citation: BMC Chemistry 2024 18:219
    Content type: Research Published on:

  16. A straightforward and sensitive spectrofluorimetric approach was established for the determination of heptaminol hydrochloride (HTM-HCl) based on the derivatization of the drug through its reaction with 5-dime...

    Authors: Mahmoud Abdelgaleel, Dalia M. Nagi, Mohamed Oraby, Sayed M. Derayea and Pakinaz Y. Khashaba
    Citation: BMC Chemistry 2024 18:218
    Content type: Research Published on:

  17. In recent years, there has been considerable interest in using amino acids like tryptophan (Trp) and tyrosine (Tyr) as biomarkers for various diseases, including type 2 diabetes mellitus (T2D). In diseases lik...

    Authors: Rania M. Kamel, Fatma A. M. Abdel-aal, Fardous A. Mohamed and Abdel-Maaboud I. Mohamed
    Citation: BMC Chemistry 2024 18:217
    Content type: Research Published on:

  18. Methamphetamine, pseudoephedrine, and related drugs are among the first drugs used for the stimulation of the central nervous system. In this study, two adsorbents based on graphene oxide (GO) were synthesized...

    Authors: Nasim Nourani, Yousef Javadzadeh, Ali Shayanfar, Arezou Taghvimi, Ahad Bavili-Tabrizi and Siavoush Dastmalchi
    Citation: BMC Chemistry 2024 18:216
    Content type: Research Published on:

  20. The cardioprotective drug cyclocreatine phosphate has been awarded Food and Drug Administration-orphan drug designation for the prevention of ischemic injury to enhance cardiac graft recovery and survival in h...

    Authors: Ibrahim F. Abo-Elmagd, Amr M. Mahmoud, Medhat A. Al-Ghobashy, Marianne Nebsen, Mostafa A. Rabie, Ahmed F. Mohamed, Lamiaa A. Ahmed, Nesrine S. El Sayed, Reem K. Arafa, Robert Todd and Salwa A. Elgebaly
    Citation: BMC Chemistry 2024 18:214
    Content type: Research Published on:

  21. Bioassay-guided fractionation approach led to identification of two novel compounds; (4-(hydroxymethyl)-3-methoxy-1H-pyrazol (1) and mycalene (2), alongside with four known metabolites; octadecane (3), hexatriaco...

    Authors: Asmaa Abo Elgoud Said, Islam M. Abdel-Rahman, Yaser A. Mostafa, Eman Zekry Attia, Mamdouh Nabil Samy, Usama Ramadan Abdelmohsen, Katsuyoshi Matsunami, Mostafa A. Fouad and Yaser G. Gouda
    Citation: BMC Chemistry 2024 18:213
    Content type: Research Published on:

  22. Parkinson's disease (PD) emerges as a notable health concern among the elderly population. Safinamide mesylate (SAF) is a novel and emerging add-on therapy in PD treatment. The stability of innovative drug for...

    Authors: Engy A. Ibrahim, Samah S. Saad, Maha A. Hegazy, Laila E. Abdel Fattah and Hoda M. Marzouk
    Citation: BMC Chemistry 2024 18:212
    Content type: Research Published on:

  23. Epoxy is a widely used thermosetting resin recognized for its exceptional performance in adhesives, coatings, and various other applications, attributed to its high tensile strength, stiffness, electrical perf...

    Authors: Soliman Mehawed Abdellatif Soliman, Mohab Abdelhakim and Magdy Wadid Sabaa
    Citation: BMC Chemistry 2024 18:211
    Content type: Research Published on:

  24. The NLRP3 inflammasome plays a crucial role in inflammatory responses, particularly in alcohol-related liver disease (ALD). Given that NLRP3 has emerged as a potential therapeutic target for ALD, the developme...

    Authors: Tao Jiang, Shijing Qian, Jinhong Xu, Shuihong Yu, Yang Lu, Linsheng Xu and Xiaosi Yang
    Citation: BMC Chemistry 2024 18:210
    Content type: Research Published on:

  25. Nowadays, there is a need to expand the bank of spectrophotometric methods for the determination of perindopril in dosage forms for the purposes of routine pharmaceutical analysis, which would be simple, expre...

    Authors: Liudmyla Halka, Tetyana Kucher, Marjan Piponski, Liubomyr Kryskiw, Nadiya Zarivna, Mariana Horyn, Nataliia Horlachuk, Khrystyna Duve and Liliya Logoyda
    Citation: BMC Chemistry 2024 18:209
    Content type: Research Published on:

  26. New Series of N-Manniche bases 3,4 (a-c) and 5,6 (a-b) were synthesized through the reaction of benzaldehyde and amine with 3-methyl-4-(aryldiazenyl)-1H-pyrazol-5-ol derivatives 2(a-c), they were fully characteri...

    Authors: Manar G. Salem, Mohamed S. Nafie, Aya A. Elzamek, Hosam A. Elshihawy, Mamdouh A. Sofan and Elham Negm
    Citation: BMC Chemistry 2024 18:208
    Content type: Research Published on:

  27. Methyldopa, a synthesized dopamine substitute with phenolic, amine, and carboxylic groups, was used to create a selective molecular imprinted polymer (MIP) for detecting formoterol fumarate dihydrate (FFD), a ...

    Authors: Hamees A. Adawy, Maha A. Hegazy, Samah S. Saad, Amr M. Bekhet and Shereen A. Boltia
    Citation: BMC Chemistry 2024 18:207
    Content type: Research Published on:

  28. Nanoparticles (NPs) as radiosensitizers present a promising strategy for enhancing radiotherapy effectiveness, but their potential is significantly influenced by the properties of their surface coating, which ...

    Authors: Elham Mansouri, Saeed Rajabpour and Asghar Mesbahi
    Citation: BMC Chemistry 2024 18:206
    Content type: Research Published on:

  29. A sustainable HPTLC-densitometric method was developed for quantitative determination of Quetiapine (QUET), Levodopa (LD) and Carbidopa (CD) in presence of Dopamine (DOP) as an internal standard. This applicab...

    Authors: Finan T. Hindam, Amal M. Abou Al Alamein, Reham M. Arafa, Neven Ahmed and Basma M. Eltanany
    Citation: BMC Chemistry 2024 18:205
    Content type: Research Published on:

  30. The regulatory role of zinc in bone formation extends to the activation of proteins associated with bone homeostasis. Furthermore, copper is well known for its antibacterial properties. This dual function unde...

    Authors: S. Sharmila, A. Saranya, M. Arulprakasajothi, R. Saranya, B. Srimanickam, Sunil Kumar Abel, Faiyaz Shakeel and Md Faiyazuddin
    Citation: BMC Chemistry 2024 18:204
    Content type: Research Published on:

  31. Gliomas, particularly glioblastoma (GBM), are highly aggressive brain tumors with poor prognosis and high recurrence rates. This underscores the urgent need for novel therapeutic approaches. One promising targ...

    Authors: Yihuan Zhao, Xiaoyu He and Qianwen Wan
    Citation: BMC Chemistry 2024 18:203
    Content type: Research Published on:

  32. Arsenic species have been known for their toxic impact on human. Therefore, removal of such pollutant requires efficient and effective removal methodology from polluted water. In this study, bismuthene quantum...

    Authors: Saad S. M. Hassan, Mohamed E. Mahmoud, Rana M. Tharwat and Amir M. Abdelfattah
    Citation: BMC Chemistry 2024 18:202
    Content type: Research Published on:

  33. Novel univariate and chemometrics-aided UV spectrophotometric methods were tailored to undergo the fundamentals of green and white analytical chemistry for the simultaneous estimation of a ternary mixture of o...

    Authors: Hussein N. Ghanem, Asmaa A. El-Zaher, Sally T. Mahmoud and Enas A. Taha
    Citation: BMC Chemistry 2024 18:201
    Content type: Research Published on:

  34. The availability of well-established analytical methods is crucial to cope with the fast-ongoing research for the development of new drug delivery formulations. In this work, a rapid highly green chromatograph...

    Authors: Yomna A. Salem, Ahmed Emad F. Abbas, Amgad E. Salem, Aya A. Abdella and Amal A. El-Masry
    Citation: BMC Chemistry 2024 18:200
    Content type: Research Published on:

  35. The process of removing sulfur compounds and aromatic compounds to produce clean fuel is an important and effective contribution to the processes of mitigating and adapting to climate change. In contrast, it i...

    Authors: Hamida Y. Mostafa, Ghada E. Khedr, Ard Elshifa M. E. Mohamed and Dina M. Abd El-Aty
    Citation: BMC Chemistry 2024 18:199
    Content type: Research Published on:

  36. Melanin nanoparticles (MNPs) are a type of electronegative compound that can be used as photothermal agent for cancer treatment. Nevertheless, the agglomeration of MNP, which is one of the limitations in pract...

    Authors: Xue Li, Yixuan Wang, Xinkai Geng, Jinghua Sun, Yulong Liu, Anjie Dong and Ruiping Zhang
    Citation: BMC Chemistry 2024 18:198
    Content type: Research Published on:

  37. The development of two eco-friendly analytical methods for the simultaneous determination of eight cardiovascular drugs; hydrochlorothiazide (HCT), captopril (CPL), lisinopril (LSP), valsartan (VAL), atorvasta...

    Authors: Sara S. Mourad, Magda A. Barary and Amira F. El-Yazbi
    Citation: BMC Chemistry 2024 18:197
    Content type: Research Published on:

  38. New generation of electrochemical energy storage devices (EESD) such as supercapattery is being intensively studied as it merges the ideal energy density of batteries and optimal power density of supercapacito...

    Authors: Davinder Singh, M. Pershaanaa, N. K. Farhana, Shahid Bashir, K. Ramesh and S. Ramesh
    Citation: BMC Chemistry 2024 18:196
    Content type: Research Published on:

  39. Ectoine (ECT) has recently gained considerable interest in the healthcare sector due to its promising therapeutic benefits in a variety of human disorders. This research aimed to quantify the ECT plasma level ...

    Authors: Mahmoud Rabee, Ragab A. M. Said and Ibrahim A. Naguib
    Citation: BMC Chemistry 2024 18:195
    Content type: Research Published on:

  40. Povidone-iodine is identified as one of the widely applicable antiseptic reagents for treatment of skin infection and wound healing. Controllable releasing of povidone-iodine is extensively required for healin...

    Authors: Moataz Morad, Seraj O. Alzahrani, Albandary Almahri, Ibrahim S. S. Alatawi, Kamelah S. Alrashdi, Kholood M. Alkhamis, Hatun H. Alsharief and Nashwa M. El-Metwaly
    Citation: BMC Chemistry 2024 18:194
    Content type: Research Published on:

  41. The current work looks at the inhibitory effects of a diolefinic dye, namely 1,4-bis((E)-2-(3-methyl-2,3-dihydrobenzo[d]thiazol-2-yl) vinyl) benzene iodide salt, in relation to CS corrosion mitigation in hydro...

    Authors: Marwa N. El-Nahass, Tarek A. Fayed, Mohammed M. El-Gamil and Abd El-Aziz S. Fouda
    Citation: BMC Chemistry 2024 18:193
    Content type: Research Published on:

  42. Tetracyclines family is considered as the first-line antibiotic drugs for food animals. Formulating bromhexine (BR) with oxytetracycline (OTC) improved the antibacterial activity of OTC, besides it is consider...

    Authors: Marco M.Z. Sharkawi, Mark T. Safwat and Nada S. Abdelwahab
    Citation: BMC Chemistry 2024 18:192
    Content type: Research Published on:

  43. The COVID-19 pandemic has prompted the medical systems of many countries to develop effective treatments to combat the high rate of infection and death caused by the disease. Within the array of proteins found...

    Authors: Faezeh Bazzi-Allahri, Fereshteh Shiri, Shahin Ahmadi, Alla P. Toropova and Andrey A. Toropov
    Citation: BMC Chemistry 2024 18:191
    Content type: Research Published on:

  44. Budesonide (BDS) a steroid-based anti-inflammatory drug widely prescribed for various diseases, has a low aqueous solubility. In this study, we investigated cosolvency approach to study the thermodynamic speci...

    Authors: Esmaeil Mohammadian, Mina Dashti, Fleming Martinez and Abolghasem Jouyban
    Citation: BMC Chemistry 2024 18:190
    Content type: Research Published on:

  45. Delivering anticancer drugs to the appropriate site within the body poses a critical challenge in cancer treatment with chemotherapeutic agents like doxorubicin (DOX). Magnetic graphene oxide (GO) nanosheets w...

    Authors: Amir Reza Sarikhani, Mehdi Abedi, Samira Sadat Abolmaali, Sedigheh Borandeh and Ali Mohammad Tamaddon
    Citation: BMC Chemistry 2024 18:189
    Content type: Research Published on:

  47. Excessive activity of the tyrosinase enzyme during melanogenesis results in hyperpigmentation in the skin. To address this issue, there is a need to develop effective tyrosinase inhibitors as a treatment for h...

    Authors: Mohammad Azimi, Zahra Najafi, Asrin Bahmani, Gholamabbas Chehardoli and Aida Iraji
    Citation: BMC Chemistry 2024 18:187
    Content type: Research Published on:

  49. The rapid uprising technologies of smartphone applications and software introduced a new era for analytical detection techniques. It has transformed bench-top laboratory methods into simpler ones depending on ...

    Authors: Eman M. Moaaz, Ezzat M. Abdel-Moety, Mamdouh R. Rezk and Ahmed S. Fayed
    Citation: BMC Chemistry 2024 18:185
    Content type: Research Published on:

  50. In this study, synthesis and assessment of the corrosion inhibition of four new binary heterocyclic pyrimidinones on CS in 1.0 M hydrochloric acid solutions at various temperatures (30–50 °C) were investigated...

    Authors: Hajar A. Ali, Ahmed. A. El-Hossiany, Ashraf S. Abousalem, Mohamed A. Ismail, Abd El-Aziz S. Fouda and Eslam A. Ghaith
    Citation: BMC Chemistry 2024 18:182
    Content type: Research Published on:
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BMC Chemistry

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