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Table 5 System suitability parameters of the developed TLC method for the determination of propranolol and methimazole

From: Thyrotoxicosis antidote assay along with concurrent medication; chromatographic and environmental issues

Parameters

Plasma

PRP

MTZ

HCA

Reference value [38]

Retardation factor (Rf)

0.07

0.19

0.67

0.81

–

Capacity factor (K')

–

4.26

0.49

0.23

0–10

Symmetry factor

–

1.00

1.04

1.00

 ~ 1

Resolution (Rs)

5.63

10.90

2.52

R > 1.5

Selectivity (α)

3.12

8.69

2.13

α > 1