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Fig. 3 | BMC Chemistry

Fig. 3

From: Impurity profiling of paracetamol toxic impurities in pharmaceutical combination with ibuprofen and chlorzoxazone using HPLC and TLC densitometric methods

Fig. 3

HPLC chromatogram of p-aminophenol (2.0 μg/mL, tR = 3.7), paracetamol (20.0 μg/mL, tR = 5.5), p-nitrophenol (2.0 μg/mL, tR = 6.9), ibuprofen (20.0 μg/mL, tR = 8.3), chlorzoxazone (20.0 μg/mL, tR = 9.6), and p-chloroacetanilide (2.0 μg/mL, tR = 11.0) using an Xterra C8 column (150 × 4.6 mm, 5 µm), mobile phase composed of acetonitrile and buffer (pH = 7.5) at a ratio of 30.0: 70.0 (v/v) with a flow rate of 0.7 mL/min and detection at 220.0 nm

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BMC Chemistry

ISSN: 2661-801X

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