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Table 2 Experimental (xe) and ideal solubility (xidl) values of RCB in different {PEG 400 + water} mixes (PEG 400 mass fraction m = 0.0–1.0) at 293.2–313.2 K and 101.1 kpa

From: Temperature-dependent solubilization and thermodynamic characteristics of ribociclib in varied {PEG 400 + water} combinations

ma

xeb

T = 293.2 K

T = 298.2 K

T = 303.2 K

T = 308.2 K

T = 313.2 K

0.0

1.14 × 10− 5

1.41 × 10− 5

1.68 × 10− 5

2.11 × 10− 5

2.41 × 10− 5

0.1

2.29 × 10− 5

2.84 × 10− 5

3.41 × 10− 5

4.29 × 10− 5

4.90 × 10− 5

0.2

4.51 × 10− 5

5.59 × 10− 5

6.79 × 10− 5

8.51 × 10− 5

9.89 × 10− 5

0.3

8.91 × 10− 5

1.13 × 10− 4

1.39 × 10− 4

1.74 × 10− 4

2.02 × 10− 4

0.4

1.78 × 10− 4

2.24 × 10− 4

2.73 × 10− 4

3.42 × 10− 4

4.05 × 10− 4

0.5

3.51 × 10− 4

4.40 × 10− 4

5.47 × 10− 4

6.82 × 10− 4

8.17 × 10− 4

0.6

6.90 × 10− 4

8.68 × 10− 4

1.11 × 10− 3

1.41 × 10− 3

1.72 × 10− 3

0.7

1.39 × 10− 3

1.74 × 10− 3

2.20 × 10− 3

2.74 × 10− 3

3.37 × 10− 3

0.8

2.72 × 10− 3

3.43 × 10− 3

4.37 × 10− 3

5.47 × 10− 3

6.73 × 10− 3

0.9

5.37 × 10− 3

6.79 × 10− 3

8.71 × 10− 3

1.12 × 10− 2

1.38 × 10− 2

1.0

1.05 × 10− 2

1.34 × 10− 2

1.73 × 10− 2

2.17 × 10− 2

2.73 × 10− 2

xidl

2.86 × 10− 1

2.99 × 10− 1

3.13 × 10− 1

3.27 × 10− 1

3.41 × 10− 1

  1. aThe uncertainties u are u(T) = 0.15 K, u(m) = 0.0007, and u(p) = 2 kPa, and bthe relative uncertainty ur in solubility is ur(xe) = 0.05
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BMC Chemistry

ISSN: 2661-801X

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