Novel spectrophotometric methods for concurrent assessment of duloxetine and avanafil in their binary mixture using derivative spectroscopy: greenness-blueness evaluation

Table 1 Statistical data of some analytical parameters of the proposed methods

Parameters	Method I (second derivative)		Method II (dual wavelength 1st derivative)
Parameters	DLX	AVN	DLX	AVN
Linear range (µg/mL)	0.5–12	1–12	1–10	1–10
Slope ± SD	0.0033 ± 2.3E-05	0.0007 ± 7.83E-06	98.20 ± 0.89	9.44 ± 0.10
Intercept ± SD	0.0003 ± 0.00015	0.0003 ± 5.76E-05	-22.76 ± 5.43	11.63 ± 0.61
r *	0.9999	0.9998	0.9998	0.9998
Number of determinations	5	5	5	5
LOQ (µg/mL)	0.15	0.27	0.17	0.22
LOQ (µg/mL)	0.45	0.82	0.51	0.68

ISSN: 2661-801X