Development of UV-Chemometric techniques for resolving the overlapped spectra of aspirin, caffeine and orphenadrine citrate in their combined pharmaceutical dosage form

Table 1 Chemometric design for calibration and validation sets for ASP, CAF & ORP

Set	Calibration set			Set	Calibration set			Set	Validation set
Mix No.	ASP	CAF	ORP	Mix No.	ASP	CAF	ORP	Mix No.	ASP	CAF	ORP
C1	12	12	12	C10	12	16	16	V1	8	16	10
C 2	12	8	8	C11	16	16	8	V 2	10	16	12
C 3	8	8	16	C12	8	14	8	V 3	10	14	16
C 4	16	10	16	C13	8	12	14	V 4	16	14	12
C 5	16	12	10	C14	12	14	14	V 5	16	8	14
C 6	12	10	10	C15	14	14	10	V 6	14	8	12
C 7	10	10	14	C16	10	8	10	V 7	14	10	8
C 8	14	16	14	C17	10	12	8	V 8	8	10	12
C 9	14	12	16

• Concentrations used for ASP, CAF and ORP are 8 ug, 10 ug, 12 ug, 14 ug and 16 ug for each

ISSN: 2661-801X