Functionalized novel carbon dots from bell pepper seeds for sustainable green Edoxaban quantification

BMC Chemistry

Table 1 Regression parameters and validation sheet for determination of EDO standard solution by the proposed method

Parameters	Microwave CDs	Plate CDs
Excitation wavelength	310 nm	310 nm
Emission Wavelength	409 nm	409 nm
Linearity range	0.80–20.00 µg/mL	0.80–20.00 µg/mL
Slope	14.41	22.31
Coefficient of determination (R2)	0.9996	0.9994
Standard deviation of the residuals (S_y/x)	2.30	3.84
Limit of detection (LOD) ^a	0.23 µg/mL	0.22 µg/mL
Limit of quantitation (LOQ) ^b	0.69 µg/mL	0.72 µg/mL
Mean %recovery ^c ± SD	100.11 ± 1.35	100.05 ± 1.61
Intra-day precision ^d	100.55 ± 0.86	98.55 ± 0.98
Inter-day precision ^e	101.31 ± 0.59	100.35 ± 1.15

^a LOD = 3.3σ/ S (σ is the standard deviation of the response and S the slope of the calibration curve)
^b LOQ = 10σ/ S (σ is the standard deviation of the response and S the slope of the calibration curve)
^c Average recoveries of six different concentrations
^d Average recoveries of three replicates for three different concentrations (0.80, 10.00, and 20.00 µg/mL), on the same day
^e Average recoveries of three replicates for three different concentrations (0.80, 10.00, and 20.00 µg/mL), on different days

ISSN: 2661-801X