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Table 1 Formulation composition of artemether-loaded SRMS-based chitosan-coated SLNs

From: Solidified reverse micellar solution-based chitosan-coated solid lipid nanoparticles as a new approach to enhance oral delivery of artemether in malaria treatment

Batch code

Lipid matrix (%w/w)

Artemether (%w/w)

Tween® 80 (%w/w)

Soluplus® (%w/w)

Sorbic acid (%w/w)

Chitosan (%w/w)

Distilled water q.s. to 100%w/w

X1

10.0

1.0

1.0

4.0

0.1

0.0

100.0

Y1

10.0

1.0

1.0

4.0

0.1

0.5

100.0

X0

10.0

0.0

1.0

4.0

0.1

0.0

100.0

Y0

10.0

0.0

1.0

4.0

0.1

0.5

100.0

  1. X0 free neutral SRMS-based SLNs, Y0 free chitosan-coated SRMS-based SLNs, X1 artemether-loaded unmodified SRMS-based SLNs, and Y1 artemether-loaded chitosan-coated SRMS-based SLNs