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Fig. 11 | BMC Chemistry

Fig. 11

From: Solidified reverse micellar solution-based chitosan-coated solid lipid nanoparticles as a new approach to enhance oral delivery of artemether in malaria treatment

Fig. 11

Histopathological results of a artemether suspension (sample 21), b artemether-loaded chitosan-coated SRMS-based SLNs (sample 2) and c unloaded chitosan-coated SRMS-based SLNs (placebo) (sample 23). Kidney section of mice treated with the formulations containing artemether (A–C). Liver section of mice treated with the formulations containing artemether (D–F). (H&E 100 ×). Left panel: Photomicrograph of the kidney of rats showing the renal corpuscles (black arrows) comprising the Bowman’s capsule (white arrow) and the glomerulus (G). Note the myriads of normal renal tubules, surrounding the Bowman’s capsules in all the groups. (H, E 100 ×). Right panel: Photomicrograph of the liver of mice showing normal plates of hepatocytes (thin black arrows) and central venules (v). Note the presence of congested central veins and vacuolar degeneration of the hepatocytes in placebo group. (H, E 100 ×)

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BMC Chemistry

ISSN: 2661-801X

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