Fig. 6

Cytotoxicity effect of As NPs, MTF@As NPs, arsenic trioxide (As₂O₃), and metformin on (a) MCF-7 and (b) NIH3T3 cell lines using MTT assay after 24 h incubation at 37 °C with 5% co₂. Metformin showed significantly lower cytotoxic effects on MCF-7 and 3T3 cells than MTF@As NPs, As NPs, and As2O3 (p < 0.05). All data represented as mean ± SD of three experiments on different days (P-value < 0.05 considered as *)