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Table 2 Laboratory-prepared mixtures of Letrozole in presence of its alkali-induced degradation products using the proposed spectrophotometric methods

From: Stability-indicating spectrophotometric manipulations for the determination of Letrozole in the presence of its alkali-induced degradation products; towards whiteness and ChlorTox scale perspectives

Ratio %

* Recovery %

LTZ: Alkali-induced degradation products

D2

RD

DD1

9: 1

100.88

98.44

101.56

8: 2

100.45

99.02

100.55

7: 3

101.34

101.62

101.98

6: 4

101.27

101.80

99.81

5: 5

101.17

101.41

101.09

4: 6

101.02

100.61

98.38

3: 7

100.76

101.10

100.47

2: 8

100.25

98.91

100.10

1: 9

91.09 **

89.41 **

90.21 **

Recovery

(Mean % ± SD)

100.89 ± 0.389

100.36 ± 1.361

100.49 ± 1.122

  1. * Average of three determinations
  2. ** Rejected values