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Table 4 Determination of pantoprazole and domperidone in Pantosec-D® tablets by the proposed and the reported methods

From: A green three-ratio manipulating spectrophotometric approaches for the determination of a binary mixture of pantoprazole and domperidone

 

Mean ± %RSD

PAN

DOM

RD

1DD

MC

Reported method

RD

1DD

MC

Reported method

Pantosec-D tab.a

100.92 ± 0.984

100.22 ± 0.614

99.35 ± 1.423

101.09 ± 0.823

100.63 ± 0.676

100.14 ± 1.568

99.22 ± 1.422

100.87 ± 1.1.069

Standard additionb

99.32 ± 0.845

100.53 ± 0.749

100.61 ± 0.918

99.20 ± 1.347

100.11 ± 0.785

100.22 ± 0.669

Student’s t-testc

(2.306)

0.300

0.297

2.294

0.425

0.855

2.066

F-valuec (6.388)

1.425

1.794

3.156

2.513

2.123

1.766

  1. aFive measurements were averaged
  2. bThree measurements were averaged
  3. cThe numbers in parenthesis are the “t” and “F” tabulated values at (P = 0.05)