Table 11 Greenness assessment of the developed chromatographic method using the ESA, ComplexMoGAPI, and AGREE scoring techniques
Developed HPLC method | ESA | Penalty points (pp) | ComplexMoGAPI pictogram |
|---|---|---|---|
Reagents | TEA (0.07 ml) Pictogram (4) Signal word:Danger | 8 |
|
Tetrabutylammonium hydrogen sulphate (0.18 ml) Pictogram (2) Signal word: Danger | 4 | ||
Phosphoric acid (< 10 ml) Pictogram (1) Signal word: Danger | 2 | ||
Potassium phosphate Pictogram (0) Signal word: Non-hazardous | 0 | ||
Acetonitrile (1.47 ml) Pictogram (2) Signal word: Danger | 4 | ||
Instrument | LC ≤ 1.5 KWh/sample | 1 | |
Waste (15 ml) | 5 | ||
Occupational hazard | 0 | ||
Total pp: 24 Analytical eco scale: 76 “Excellent green analysis” | |||
AGREE pictogram | BAGI pictogram | ||
|
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