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Table 3 The antibacterial activity of the 2-(aryl)benzo[d]imidazo[2,1-b]thiazole-7-sulfonamide derivatives (5a-5h)

From: Design, synthesis, biological evaluation, and computational insights of 2-(Aryl)benzo[d]imidazo[2,1-b]thiazole-7-sulfonamide derivatives as potent antitubercular and antibacterial agents

Compounds

The antibacterial activity in MIC (μg/mL)

E. coli (ATCC 8739)

K. pneumoniae (ATCC 4352)

S. aureus (ATCC 6538)

B. subtilis (ATCC 6051)

S. aureus (ATCC 33591)

5a

25

25

12.5

12.5

12.5

5b

25

25

25

25

25

5c

25

25

25

25

25

5d

25

25

25

25

25

5e

25

25

12.5

12.5

12.5

5f

12.5

12.5

6.25

6.25

25

5g

25

25

25

25

25

5h

25

25

6.25

6.25

12.5

Ciprofloxacin

1.25

1.25

1.25

1.25

1.25