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Table 2 The antitubercular activity of the 2-(aryl)benzo[d]imidazo[2,1-b]thiazole-7-sulfonamide derivatives (5a-5h) against M. tuberculosis (H37 RV strain) using microplate Alamar Blue assay

From: Design, synthesis, biological evaluation, and computational insights of 2-(Aryl)benzo[d]imidazo[2,1-b]thiazole-7-sulfonamide derivatives as potent antitubercular and antibacterial agents

Compounds

MIC (µg/mL)

5a

6.25

5b

1.6

5c

6.25

5d

1.6

5e

12.5

5f

3.125

5g

6.25

5h

1.6

Isoniazid

1.6

Ethambutol

1.6

Pyrazinamide

3.125

Rifampicin

0.8

Streptomycin

0.8

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BMC Chemistry

ISSN: 2661-801X

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