New tetrahydroisoquinolines bearing nitrophenyl group targeting HSP90 and RET enzymes: synthesis, characterization and biological evaluation

Table 1 Inhibition activity in one spot 100 µg/ml concentration of all compounds against normal skin cell line HSF in compared with Doxorubicin

Compd.no	Inhibition percent of HSF cell line	Compd.no	Inhibition percent of HSF cell line
3	52	8a	59
4	50	8b	50
5	70	9b	58
10	56	Doxorubicin	60
2a	48
6a	56
7a	55

ISSN: 2661-801X