Ecofriendly and smart spectrophotometric approaches for synchronized analysis of two antipsychotic drugs, fluoxetine and olanzapine: application to combined tablet dosages with assessment of method greenness

Table 1 The statistical parameters of the proposed methods for determination of the studied drugs

Parameter	Ratio substruction		Dual λ	Abs. factor
	OLZ	FLX	FLX	OLZ
Linear range (µg mL^− 1)	2–12	4–24	4–30	5–15
Slope	0.069	0.038	0.037	0.057
SD of slope (S_b)	0.0004	0.0002	0.0002	0.0003
Intercept	0.0082	-0.0008	0.0024	0.0062
SD of the intercept (S_a)	0.0029	0.0026	0.0036	0.0027
Correlation coefficient r²	0.9994	0.9996	0.9996	0.9998
Determination coefficient	0.9997	0.9998	0.9998	0.9998
SD of residuals (S_{y, x})	0.006	0.006	0.006	0.003
LOD (µg mL^− 1)	0.14	0.23	0.32	0.16
LOQ (µg mL^− 1)	0.41	0.68	0.99	0.48

^a Number of determinations is 6, LOD: Limit of detection, LOQ: Limit of quantitation

ISSN: 2661-801X