Table 3 Results achieved by applying the proposed colorimetric method for the quantitative estimation of ipratropium and fenoterol in their pharmaceutical formulation and application of standard addition technique
Pharmaceutical formulation | Colorimetric method | ||||
|---|---|---|---|---|---|
Drug (µg/mL) | %Found ± SD* | Standard Addition Technique | |||
Claimed (µg/mL) | Pure added (µg/mL) | %Recovery of the pure added* | |||
Atrovent® comp HFA inhaler solution (Each metered dose is labeled to contain 20.0 µg IPR and 50.0 µg FEN) (BN. 104604) | IPR (8) | 98.00 ± 1.20 | 12 | 10.0 | 98.88 |
12.0 | 101.25 | ||||
24.0 | 100.90 | ||||
|  | Mean ± SD | 100.35 ± 1.278 | |||
FEN (20) | 98.70 ± 0.93 | 12 | 10.0 | 100.67 | |
12.0 | 100.00 | ||||
24.0 | 99.86 | ||||
|  | Mean ± SD | 100.18 ± 0.431 | |||