Table 2 Determination of AM, PE and ID in Triplixam^® Tablets* by the proposed spectrophotometric methods and application of standard addition technique

Dosage form

13.87 µg AM, 10 µg PE,

and

2.5 µg ID

AM

PE

ID

Direct method

Found amount^a

% R^a

Method

Found amount^a

% R^a

Method

Found amount^a

% R^a

14.06 ± 0.05

101.37 ± 0.33

2nd der.

10.06 ± 0.03

100.62 ± 0.29

1st der.

2.52 ± 0.02

100.65 ± 0.66

RD

10.08 ± 0.02

100.82 ± 0.19

RD

2.51 ± 0.01

100.25 ± 0.02

DW

10.15 ± 0.06

101.53 ± 0.60

DW

2.54 ± 0.02

101.47 ± 0.78

Standard addition

Direct method

DW method

DW method

Added amount

Found amount^a

% R^a

Added amount

Found amount^a

% R^a

Added amount

Found amount^a

% R^a

4

3.96 ± 0.05

98.96 ± 1.13

10

9.97 ± 0.06

99.68 ± 0.60

2

1.99 ± 0.02

99.84 ± 0.98

10

9.92 ± 0.05

99.22 ± 0.45

40

39.90 ± 0.12

99.75 ± 0.30

5

5.09 ± 0.04

101.86 ± 0.78

20

20.31 ± 0.05

101.56 ± 0.23

80

78.75 ± 0.12

98.44 ± 0.15

15

14.98 ± 0.05

99.87 ± 0.35