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Table 4 Robustness of the proposed methods

From: Novel ecofriendly spectrophotometric methods for the determination of six dihydropyridines calcium channel blockers through derivatization with sulfophtalein dye: application to tablet analysis

Method parameters

Recovery* ± SD

AML

LAC

LAML

NIF

NIM

NIT

Stability of solutions, min

 15

100.21 ± 1.5

100.92 ± 1.11

100.12 ± 1.23

101.01 ± 0.69

99.87 ± 0.98

100.12 ± 0.93

 30

99.97 ± 1.56

99.78 ± 0.77

100.69 ± 1.09

98.86 ± 0.36

100.09 ± 1.42

100.42 ± 0.98

 60

99.69 ± 0.88

101.21 ± 0.39

99.5 ± 0.4

100.56 ± 0.09

99.53 ± 1.13

100.14 ± 1.3

Volume of reagent, mL

 0.9

100 ± 1.54

100.81 ± 0.66

99.62 ± 1.43

100.93 ± 0.83

100.12 ± 0.93

99.97 ± 0.8

 1.0

98.86 ± 0.46

99.9 ± 1.29

100.68 ± 0.55

99.43 ± 0.66

100.42 ± 0.98

100.16 ± 1.03

 1.1

98.91 ± 0.73

100.12 ± 0.98

99.5 ± 0.91

100.25 ± 1.55

100.14 ± 1.3

100.3 ± 1.22

Time of reaction, min

 5

100.12 ± 1.45

100.76 ± 1.26

100.23 ± 1.77

98.9 ± 0.73

99.85 ± 1.35

100.51 ± 1.2

 10

99.8 ± 1.34

100.44 ± 0.98

99.53 ± 1.36

99.81 ± 0.59

100.83 ± 1.25

99.11 ± 0.76

 15

99.35 ± 0.76

99.64 ± 0.91

100.54 ± 1.48

100.55 ± 0.48

99.7 ± 1.02

99.27 ± 1.3

  1. *Average of the three results