Assessment of greenness, blueness, and whiteness profiles of a validated HPLC-DAD method for quantitation of Donepezil HCl and Curcumin in their laboratory prepared co-formulated nanoliposomes

Table 5 Determination of DPZ and CUR in their laboratory prepared nanoliposome formulation using the suggested HPLC-DAD and refrence methods

Nanoliposome Formulation	Concentration Taken (µg/ml)	Concentration Found (µg/ml)	Suggested Method % Found*	Reference Method % Found*[46,47]
DPZ	1	0.998	99.8	99.30
	50	50.10	100.2	101.20
	100	98.80	98.8	98.30
Mean ± S. D			99.6 ± 0.72	99.60 ± 1.47
%RSD			0.72	1.48
t-test			2.353(3.182) 3.804(19.00)
F-test			2.353(3.182) 3.804(19.00)
CUR	1	1.0145	101.45	102.00
	50	49.8500	99.7	101.34
	100	100.4000	100.4	98.99
Mean ± S. D			100.52 ± 0.89	100.78 ± 1.58
%RSD			0.88	1.57
t-Test			0.249(2.776) 3.226(19.00)
F-Test			0.249(2.776) 3.226(19.00)

^** The theoretical t and F values at (P = 0.05) are enclosed in parentheses [48]

ISSN: 2661-801X