Table 5 The designed molecules and their predicted dual-target activities
PREDICTIONSa, b,c, d | |||||||
|---|---|---|---|---|---|---|---|
ID | cj | PredIAi(cj) | ProbAct(%) | ID | cj | PredIAi(cj) | ProbAct(%) |
AMD-01 | c01 | 1 | 66.32 | AMD-03 | c01 | 1 | 62.06 |
AMD-01 | c02 | -1 | 45.16 | AMD-03 | c02 | 1 | 62.87 |
AMD-01 | c03 | 1 | 81.34 | AMD-03 | c03 | 1 | 81.98 |
AMD-01 | c04 | -1 | 30.67 | AMD-03 | c04 | -1 | 35.10 |
AMD-01 | c05 | 1 | 70.80 | AMD-03 | c05 | 1 | 50.68 |
AMD-01 | c06 | -1 | 47.31 | AMD-03 | c06 | 1 | 56.54 |
AMD-02 | c01 | 1 | 57.73 | AMD-04 | c01 | 1 | 69.69 |
AMD-02 | c02 | 1 | 75.61 | AMD-04 | c02 | 1 | 84.38 |
AMD-02 | c03 | 1 | 79.94 | AMD-04 | c03 | 1 | 61.36 |
AMD-02 | c04 | -1 | 39.77 | AMD-04 | c04 | 1 | 65.81 |
AMD-02 | c05 | -1 | 40.66 | AMD-04 | c05 | -1 | 35.44 |
AMD-02 | c06 | 1 | 63.58 | AMD-04 | c06 | 1 | 55.30 |