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Table 2 The physicochemical properties of drugs used in the treatment of multiple sclerosis

From: A computational approach to drug design for multiple sclerosis via QSPR modeling, chemical graph theory, and multi-criteria decision analysis

Properties

Enthalpy of Vaporization

Flash Point

Molar weight

Polarizability

Molar Volume

Complexity

Cladribine

87

285

285.69

25.3

140.2

338

Teriflunomide

69.9

202.3

270.21

24

189.7

426

Mitoxantrone

122.8

441.1

444.5

47.5

306.5

571

Masitinib

  

498.6

58.4

389.3

696

Fingolimod

42.9

91.1

144.12

13.3

128.2

141

Dimethyl Fumarate

78.4

243.8

307.5

37.1

302.4

258

Laquinimood

79

247

356.8

38.1

255.7

571

Diroximel Fumarate

69.8

220.5

255.22

23.1

193.5

384

Siponimod

94.2

317.9

516.6

53.9

413.6

777

Ozanimod

100.4

345.9

404.5

43.9

309.2

609

Ponesimod

101.8

351.7

461

49.1

352.9

674

Cyclophosphamide

57.9

157.1

261.08

23

195.7

212