Table 4 Application of the suggested method for determination of TIR in Clograstate dosage form:
Parameters | Added (ng/mL) | Found (ng/mL) | Bais% | Recovery (%)* | HPLC (5) |
|---|---|---|---|---|---|
Clograstat® (12.5 mg /50 mL) 200 ng/mL (4 × 10–4 M) | 100 | 300.03 | 0.03 | 100.03 | 99.99 |
300 | 499.95 | 0.017 | 99.98 | 99.97 | |
500 | 700.1 | 0.02 | 100.02 | 100.01 | |
Mean* | 100.02 | 100.00 | |||
Variance | 0.000492 | 0.000292 | |||
SD | 0.022174 | 0.017078 | |||
Student-t-test** (1.943) | 1.429 | ||||
P | 0.202884 | ||||
F-test (9.277)** | 1.686 |