Fig. 1

(A) the chemical structures of selumetinib (SEL) and 2,3-dichloro-5,6-dicyano-1,4-benzoquinone (DDQ). (B) the absorption spectra of SEL (1.1 × 10− 3 M) and the reaction mixtures (SEL-DDQ) containing varying concentrations of SEL with a fixed concentration of DDQ (8.8 × 10− 3 M). All solutions were in acetonitrile