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Fig. 4 | BMC Chemistry

Fig. 4

From: Development of an HPLC–UV method for quantification of posaconazole in low-volume plasma samples: design of experiments and machine learning models

Fig. 4

a Chromatograms of IS (0.5 μg/mL) and PCZ (1 μg/mL) in methanol, determination of the LOQ of PCZ in plasma, and 6 individual blank plasma samples, b Stability study results obtained for PCZ samples (mean ± SEM, n = 3), c The mean plasma concentration–time profile of PCZ-loaded nanomicelles in rats (mean ± SEM, n = 3). IS internal standard, LOQ limit of quantification, PCZ posaconazole

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