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Table 5 IC50 (µg/ml) of the tested compound 5 and doxorubicin against HCT-116 and HepG-2 cell lines using MTT assay

From: New thiophene derivatives: chemoselective synthesis, antitumor effectiveness, structural characterization, DFT calculations, Hirshfeld surface, and Fukui function analysis

 

HCT-116

HepG-2

IC50 (µg/mL)

IC50 (µg/mL)

Doxorubicin

0.49

0.36

5

12.60

7.46