BMC Chemistry

Table 2 Application of the proposed method to the determination of RIV and EDT in their raw materials

From: Bio-inspired one-pot synthesis of luminescent silver nanoparticles and its significant utility as a fluorescence nano sensor for analysis of two adjunctive COVID-19 drugs

Compound	Proposed method						Comparison method
	At 333 nm			At 485 nm			Comparison method
	Amount taken (μg/ml)	Amount found (μg/ml)	%Found*	Amount taken (μg/ml)	Amount found (μg/ml)	%Found*	Amount taken (μg/ml)	Amount found (μg/ml)	%Found*
Rivaroxaban	0.5	0.49	98.00	1	0.99	99.00	5	5.01	100.20
	1	0.99	99.00	3	2.97	99.00	7	6.91	98.71
	3	3.04	101.33	5	5.08	101.60	10	10.10	101.00
	5	4.97	99.40	7	7.00	100.00	15	14.96	99.73
	7	7.06	100.86	9	8.96	99.56
	9	8.91	99.00
	10	10.05	100.50
X⁻ ± SD			99.72 ± 1.20			99.83 ± 1.07			99.91 ± 0.96
Student's t test			0.29 (2.26) **			0.11(2.36) **
Variance ratio (F test)			1.56(8.94) **			1.23(9.12) **
Edoxaban	0.5	0.50	100	0.7	0.69	98.57	4	4.03	100.75
Edoxaban	0.5	0.50	100	1	0.99	99	4	4.03	100.75
	1	1.000	100.00	2	2.00	100.00	6	5.99	99.83
	3	2.99	99.67	3	3.01	100.33	10	10.06	100.60
	5	4.98	99.60	5	5.00	100.00
	7	7.07	101.00	7	6.98	99.71
	9	8.90	98.88
	10	10.05	100.50
X⁻ ± SD			99.95 ± 0.68			99.60 ± 0.68			100.39 ± 0.49
Student's t test			1.11(2.26) **			1.23(2.45) **
Variance ratio (F test)			1.91(19.33) **			1.91(19.25) **

^*Each result is an average value of three separate determinations
^**Values between parentheses are the tabulated t and F values respectively, at p = 0.05

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ISSN: 2661-801X

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