Table 1 Analytical parameters for the spectrophotometric determination of perindopril through derivatization with sulphophtalein dyes
Analytical parameters | BCG | BCP | BTB | BPB |
|---|---|---|---|---|
λmax, nm | 405 | 397 | 397 | 598 |
Linearity range, µg/mL | 0.44–3.96 | 3.00–7.00 | 4.00–12.00 | 0.44–3.52 |
Intercept (a) | 0.0431 | 0.0043 | 0.0348 | 0.0205 |
Slope (b) | 0.1034 | 0.0479 | 0.0413 | 0.2229 |
Correlation coefficient (r) | 0.9997 | 0.9997 | 0.9990 | 0.9996 |
S.D. of slope (Sb) | 0.0007 | 0.0005 | 0.0007 | 0.0018 |
S.D. of intercept (Sa) | 0.0017 | 0.0025 | 0.0063 | 0.0040 |
LOD, µg/mL | 0.0543 | 0.1722 | 0.5034 | 0.0592 |
LOQ, µg/mL | 0.1644 | 0.5219 | 1.5254 | 0.1795 |
Molar absorptivity, l. mol-1. cm− 1 | 8.82 × 104 | 4.41 × 105 | 5.55 × 105 | 11.86 × 104 |
Ringbom optimum concentration range, µg/mL | 1.77–3.09 | 5.00–7.00 | 6.00–8.00 | 1.32–2.65 |