Table 5 Result of optimized formulations A
Parameters | Results | |
|---|---|---|
1. Appearance | Oval biconvex film coated tablets | |
2. Color | White | |
3. Average weight (mg) | 970.0 mg ± 5% | |
4. Thickness (mm) | 9.3 ± 0.4 | |
5. Hardness (kg/cm2) | 7.1 ± 0.30 | |
6. Friability (%) | 0.52 ± 0.02 | |
7. Drug content (%) Range (90–110% of the stated amount) | 97.24 ± 1.80 |
% Drug release | ||
|---|---|---|
Time (h) | Range | Result (%) |
1 | NMT 20% | 17.28 |
6 | 47–69% | 53.59 |
12 | 65–95% | 72.93 |
20 | NLT 85% | 91.02 |