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Table 12 The mixture response surface (MRS) model constants and the MRD% for back-computed BDS solubility in the aqueous mixture of {1-propanol (1) + water (2)} at investigated temperatures from 293.2 to 313.2 K

From: Experimental measurement, thermodynamic analysis, and mathematical modeling for budesonide solubility in 1-propanol + water mixtures at T = (293.2 to 313.2) K

T (± 0.2 K)

β1

β2

β3

β4

β5

MRD%

293.2

− 2.36

− 11.85

0.024

0

13.60

10.14

298.2

− 2.19

− 11.41

0.019

0

12.79

12.77

303.2

− 2.11

− 11.29

0.020

0

12.92

10.84

308.2

− 2.04

− 11.07

0.019

0

12.79

9.28

313.2

− 2.02

− 10.94

0.018

0

12.94

10.48

Overall

     

10.70