Table 3 Recovery and matrix effect of tepotinib in rat plasma (n = 6)
From: Measurement of tepotinib by UPLC‒MS/MS and its interaction with naringenin in rats
Analyte | Concentration (ng/mL) | Recovery (%) | Matrix effect (%) | ||
|---|---|---|---|---|---|
Mean ± SD | RSD (%) | Mean ± SD | RSD (%) | ||
0.2 | 81.2 ± 10.2 | 12.6 | 98.6 ± 12.8 | 13.0 | |
Tepotinib | 40 | 85.2 ± 10.5 | 12.4 | 90.5 ± 10.3 | 11.4 |
400 | 86.9 ± 11.4 | 13.2 | 96.3 ± 2.9 | 3.0 | |