Mutation/metal deficiency in the

Table 4 Assignment of amide I band components and percentages of secondary structure contents in apo/holo WT-SOD1 and mutant

	Corresponding secondary structure	Observed negative peaks (cm⁻¹)	Relative second structure (%)
holo-WT-SOD1	β-Sheet (aggregation) or cross-β	1625	41
	α-Helix	1658	26
	β-Turn	1677	13
	Random coil	1643	21
holo-L126S	β-Sheet (aggregation) or cross-β	1625	42
	α-Helix	1660	25
	β-Turn	1677	11
	Random coil	1642	22
apo-WT-SOD1	β-Sheet (aggregation) or cross-β	1612	5
	β-Sheet (aggregation) or cross-β	1626	25
	β-Sheet (Parallel)	1636	17
	α-Helix	1660	39
	β-Turn	1673	14
apo-L126S	β-Sheet (aggregation) or cross-β	1612	5
	β-Sheet (aggregation) or cross-β	1627	36
	α-Helix	1662	27
	Random coil	1644	32

ISSN: 2661-801X