Table 3 Results obtained by applying the proposed HPLC–DAD method for the determination of Telmisartan, Chlorthalidone and Amlodipine in Telma-ACT® Tablets and application of standard addition technique
Pharmaceutical formulation | HPLC–DAD method | ||||
|---|---|---|---|---|---|
Drug | %Found ± SDa | Standard addition technique | |||
Claimed (μg/mL) | Pure added (μg/mL) | %Recovery of the pure added amountb | |||
Telma-ACT® Tablets (Each tablet was Labelled to Contain 40 mg TEL, 12.5 mg CHT & 5 mg AML) (BN: 30TTM008) | TEL | 101.46 ± 1.30 | 40 | 20.0 | 99.05 |
40.0 | 101.75 | ||||
80.0 | 100.71 | ||||
Mean ± SD | 100.50 ± 1.36 | ||||
CHT | 98.77 ± 0.77 | 12.5 | 6.25 | 98.40 | |
12.5 | 99.20 | ||||
25.0 | 100.12 | ||||
Mean ± SD | 99.24 ± 0.86 | ||||
AML | 101.35 ± 1.33 | 5 | 2.5 | 100.40 | |
5.0 | 98.00 | ||||
10.0 | 99.80 | ||||
Mean ± SD | 99.40 ± 1.25 | ||||