Table 1 Optimization of reaction of 2,5-hexadione with aniline
From: Humin-sulfuric acid as a novel recoverable biocatalyst for pyrrole synthesis in water
Entry | Cat. (g) | Solvent (mL) | Temp. (ËšC) | Time (h) | Conv. (%) |
|---|---|---|---|---|---|
1 | Humin-SO3H (0.01) | – | 30 | 2.5 | 100 |
2 | Humin-SO3H (0.01) | – | 50 | 2.5 | 100 |
3 | Humin-SO3H (0.03) | H2O (4Â mL) | R.T | 1 | 100 |
4 | Humin-SO3H (0.02) | H2O (4Â mL) | R.T | 1 | 100 |
5 | Humin-SO3H (0.01) | H2O (4Â mL) | R.T | 1 | 100 |
6 | Humin-SO3H (0.005) | H2O (4 mL) | R.T | 3 | 100 |
7 | Humin (0.01) | H2O (4Â mL) | R.T | 2.5 | 100 |
8 | Humin-SO3H (0.01) | EtOH (4Â mL) | R.T | 3 | 30 |
9 | Humin-SO3H (0.01) | CH3CN (4Â mL) | R.T | 3 | 5 |