Inhibition of DRP-1 mitochondrial mitophagy and fission by novel α-aminophosphonates bearing pyridine: synthesis, biological evaluations, and computer-aided design

Table 5 Comparison of the experimental and calculated vibrational frequencies (cm⁻¹) of α-aminophosphonates 3a–g

Band assignment (cm⁻¹)	NH/OH stretch		CH stretch aromatic		CH stretch aliphatic		C=C stretch		C=N stretch		P=O stretch		P–O–C stretch		P–CH stretch		C–Cl
Compound	Exp	Cal	Exp	Cal	Exp	Cal	Exp	Cal	Exp	Cal	Exp	Cal	Exp	Cal	Exp	Cal	Exp	Cal
3a	3492, 3392	3723, 3646	3173, 3067	3204, 3155	3002, 2938	3070, 3048	1631	1630	1602	1608	1290	1257	1023	997	746	760	628	702
3b	3482, 3375	3720, 3641	3226, 3194, 3077	3247, 3199, 3158	3023, 2981	3074, 3047	1662	1636	1602	1608	1288	1252	1069	997	733	762	637	691
3c	3469	3645	3296, 3232, 3168	3247, 3227, 3173	3061, 2986	3063, 3037	1621	1626	1610	1606	1243	1253	1040	997	746	730	634	693
3d	3442	3551	3139	3227	3043	3050	1629	1634	1565	1595	1269	1256	1082	1000	745	723	636	690
3e	3416	3652	3279, 3170	3247, 3232	3070, 2988	3153, 3045	1632	1639	1595	1609	1240	1255	1103	999	730	756	629	685
3f	3469	3649	3296, 3232	3275, 3232	3150, 3096	3142, 3072	1628	1609	1583	1583	1236	1253	1036	998	744	757	626	652
3g	3429	3647	3215, 3141	3232, 3218	3045, 2959, 2927	3168, 3063, 3047	1617	1615	1596	1607	1274	1253	1057	997	740	728	631	631

ISSN: 2661-801X