BMC Chemistry

Table 5 Application of standard addition technique for the determination of CPM in combined Lupituss CPM® syrup formulations with LCF by the proposed TLC- densitometric and spectrophotometric methods

From: Independent concentration extraction as a novel green approach resolving overlapped UV–Vis binary spectra and HPTLC-densitometric methods for concurrent determination of levocloperastine and chlorpheniramine

CPM				LCF
Mean% ± RSD	Standard addition			Mean% ± RSD	Standard addition
Mean% ± RSD	Taken μg mL⁻¹	Added μg mL⁻¹	Recovery % of added	Mean% ± RSD	Taken μg mL⁻¹	Added μg mL⁻¹	Recovery % of added
Spectrophotometric method
99.08 ± 0.75	10.0	5.0 10.0 15.0	102.32 100.15 99.56	100.31 ± 0.64	10.0	5.0 10.0 15.0	101.18 99.47 99.84
99.08 ± 0.75	Mean ± RSD%		100.68 ± 1.45	100.31 ± 0.64	Mean ± RSD%		100.16 ± 0.90
HPTLC-densitometry method
99.55 ± 1.93	1.0	0.3 2.0 3.0	101.33 98.89 100.49	99.68 ± 0.84	2.0	0.8 6.0 8.0	99.33 98.32 101.75
99.55 ± 1.93	Mean % ± RSD		100.24 ± 1.24		Mean % ± RSD		99.82 ± 1.76

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ISSN: 2661-801X

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