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Table 4 Determination of CPM with LCF in laboratory prepared mixtures by the proposed spectrophotometric method

From: Independent concentration extraction as a novel green approach resolving overlapped UV–Vis binary spectra and HPTLC-densitometric methods for concurrent determination of levocloperastine and chlorpheniramine

Ratio

CPM:LCF

UV–Vis spectrophotometric method

TLC method

Laboratory prepared mixtures (μg mL−1)

Recovery%*

Laboratory prepared mixtures (μg mL−1)

Recovery%*

CPM

LCF

CPM

LCF

CPM

LCF

CPM

LCF

1:2

5

10

98.12

102.08

4

8

99.15

98.12

1:1

20

20

101.98

98.31

2

2

100.3

101.41

3:1

30

10

101.71

98.96

3

1

99.66

99.55

2:1

20

10

100.66

101.18

4

2

100.8

98.68

5:1

25

5

101.09

99.23

4

0.8

100.71

99.74

4:1

20

5

102.31

100.48

4

1

98.97

100.2

1:5

5

25

100.05

100.93

2

10

99.21

101.11

1:3

5

15

99.87

99.45

1

3

100.23

99.02

 

Mean% ± SD

100.72 ± 1.37

100.07 ± 1.29

Mean% ± SD

99.88 ± 0.73

99.73 ± 1.15

  1. *Average of three separate determinations