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Fig. 3 | BMC Chemistry

Fig. 3

From: QbD green analytical procedure for the quantification of tolvaptan by utilizing stability indicating UHPLC method

Fig. 3Fig. 3

2D-contours (1-2-3) and 3D-response surface(4-5-6) plots showing the influence of CMPs, i.e., flow rate (A), temperature (B) mobile phase concentration (C) on retention time as the CAA. b 2D-contours (1–2-3) and 3D-response surface (4-5-6) plots showing the influence of CMPs, i.e., flow rate (A), temperature (B) mobile phase concentration (C) on tailing factor as the CAA. c 2D-contours(1–2-3) and 3D-response surface(4-5-6) plots showing the influence of CMPs, i.e., flow rate (A), temperature (B) mobile phase concentration (C) on theoretical plate as the CAA. e perturbation plot showing deviation from reference point with 1. Retention time 2. Tailing factor 3. Theoretical plate

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