Fig. 3


2D-contours (1-2-3) and 3D-response surface(4-5-6) plots showing the influence of CMPs, i.e., flow rate (A), temperature (B) mobile phase concentration (C) on retention time as the CAA. b 2D-contours (1–2-3) and 3D-response surface (4-5-6) plots showing the influence of CMPs, i.e., flow rate (A), temperature (B) mobile phase concentration (C) on tailing factor as the CAA. c 2D-contours(1–2-3) and 3D-response surface(4-5-6) plots showing the influence of CMPs, i.e., flow rate (A), temperature (B) mobile phase concentration (C) on theoretical plate as the CAA. e perturbation plot showing deviation from reference point with 1. Retention time 2. Tailing factor 3. Theoretical plate