Fig. 10
The interactions of the four drugs with M3R by nonlinear chromatography Displayed are the experimental peak profiles for atropine (a), pirenzepine (b), darifenacin (c), and solifenacin (d) on the M3R column. The top section shows these profiles with the fitted nonlinear chromatography functions, while the bottom represents the fitted nonlinear chromatography functions in isolation. Injection concentration: 0.4 mM; injection volume: 10 μL. The Y-axis has been scaled to y = Y/C0, while the X-axis, representing the retention time (X), has been scaled to x = X/t0.