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Table 6 Analysis of the pharmaceutical preparation (Plaqunil® tablets) by applying the Simultaneous equation and Q-absorbance spectrophotometric methods

From: Various techniques for resolving overlapping ultraviolet spectra of combination pharmaceutical dosage forms containing hydroxychloroquine and paracetamol

 

Simultaneous equation method

Q-absorbance method

HCQ

PAR

HCQ

PAR

 

Recovery%

 

Recovery%

 

Recovery%

  
 

Tablet

Taken (µg/mL)

Standard Added

(µg/mL)

Tablet

Added

Tablet

Taken (µg/mL)

Standard Added

(µg/mL)

Tablet

Added

Tablet

Taken (µg/mL)

Standard Added

(µg/mL)

Tablet

Added

Tablet

Taken (µg/mL)

Standard Added

(µg/mL)

Tablet

Added

 

10

5

101.87

98.88

10

5

98.71

101.34

10

5

101.98

101.01

10

5

101.19

100.86

  

10

99.91

101.24

 

10

98.07

101.47

 

10

100.49

100.41

 

10

101.89

98.30

  

15

98.98

99.62

 

15

100.01

100.92

 

15

99.69

101.84

 

15

99.77

99.07

Mean

  

100.26

100.51

  

98.93

101.24

  

100.72

100.48

  

100.95

99.41

SD

  

1.48

1.21

  

0.99

0.29

  

1.16

0.72

  

1.08

1.31