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Table 5 Extraction recovery of cytarabine HCl and dexamethasone in spiked human plasma

From: Two chromatographic methods for determination of cytarabine and dexamethazone; two co-administered drugs for the treatment of leukemia: green analytical perspective

CYT

DEX

Conc(μg/mL)a

Recovery%

Conc(μg/mL)a

Recovery%

HPLC method

   

3

101.21

3

98.45

8

98.54

8

99.97

15

100.71

15

100.21

Mean ± SD

100.27 ± 1.56

Mean ± SD

99.68 ± 0.715

HPTLC method

1

98.13

1

98.08

2

100.32

2

99.86

4

101.87

4

101.95

Mean ± SD

100.01 ± 2.03

Mean ± SD

99.95 ± 1.95

  1. a Mean of 3 determinations
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BMC Chemistry

ISSN: 2661-801X

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