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Table 2 Determination of ritonavir in laboratory prepared mixtures with nirmatrelvir using the described method

From: Higher sensitive selective spectrofluorometric determination of ritonavir in the presence of nirmatrelvir: application to new FDA approved co-packaged COVID-19 pharmaceutical dosage and spiked human plasma

Ritonavir (ng/mL)

Nirmatrelvir (ng/mL)

Ritonavir found (ng/mL)

Ritonavir [% Recovery]

3.00

9.00

2.97

99.00

4.00

12.00

4.03

100.75

5.00

15.00

5.05

101.00

6.00

18.00

5.92

98.66

Mean ± %RSD

99.85 ± 1.859