Figure 3

(a) Structure superposition of the ligated (blue) and apo (red) LAOBP conformations as calculated by the combinatorial extension algorithm. The overall RMSD between the two conformations is 3.5 Ã…. Structure superposition of the (b) large and (c) small domains is also provided. The domain specific RMSDs are 0.6 Ã… and 0.4 Ã…, respectively.