Figure 4
From: PocketPicker: analysis of ligand binding-sites with shape descriptors

Pocket detection method used in POCKET, LIGSITE and its derivatives. Grid probes are installed at the edges of an artificial grid generated around the protein (shaded area). A scanning process is applied to detect protein-solvent-protein events (POCKET and LIGSITE) or surface-solvent-surface events (LIGSITEcs and LIGSITEcsc).